Defeating Degeneration II: Brain Anatomy & Disease Under the Microscope

Sunday,
October 25, 2020, 2:00 pm

3:00 pm

Brain anatomy: Ever wondered what the different parts of the brain do? Why are mouse & rat brains smooth whereas human brains are folded? What other differences exist in brains from different animals? Together, we’ll learn what this can tell us about the relative importance of the different senses across different species.

Brain disease under the microscope: What does Alzheimer’s disease look like in the brain? What can this tell us about what is going wrong in patients? Take a 3D dive inside the brain and learn about how we can use the knowledge we gain from the microscope to assess if treatments are working.

Join scientists from Denali Therapeutics, a Bay area Biotechnology Company focused on finding cures for neurodegenerative diseases, for a microscopic view into brain structure and disease. Presented by Robert Thorne, PhD, Denali Fellow, Denali Therapeutics & Adjunct Associate Professor, University of Minnesota; Meredith Calvert, PhD, Principal Scientist Microscopy & Imaging, Denali Therapeutics.

-Human and rodent comparative brain anatomy and function (pre-recorded)

-Neurodegenerative disease under the microscope: microscopy demonstration with examples of neuropathology from human/rodent samples and beautiful 3D reconstructions of stained neural cell types in healthy vs. diseased brain (pre-recorded)

Join our live Q&A session after watching the pre-recorded video.

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At Denali Therapeutics, we are a team dedicated to defeating degeneration. Neurodegenerative diseases affecting the brain and spinal cord are among the largest medical challenges of our time. Recent groundbreaking scientific insights into the genetic causes and biological processes underlying this class of disorders (e.g. Alzheimer’s disease, Parkinson’s disease, ALS) offer an unprecedented opportunity for the discovery and development of effective medicines. At Denali, we are passionate about solving problems with rigorous science and translational medicine. We have joined together to discover and develop new therapeutics that will change the lives of patients suffering from neurodegenerative disease.
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